Drug susceptibility profile and pathogenicity of H7N9 influenza virus (Anhui1 lineage) with R292K substitution

Neuraminidase inhibitors (NAIs) are the only available licensed therapeutics against human H7N9 influenza virus infections. The emergence of NAI-resistant variants of H7N9viruses with an NA R292K mutation poses a therapeutic challenge. A comprehensive understanding of the susceptibility of these vir...

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Pubblicato in:Emerg Microbes Infect
Autori principali: Zhang, Xiaonan, Song, Zhigang, He, Jing, Yen, Hui-Ling, Li, Jianhua, Zhu, Zhaoqin, Tian, Di, Wang, Wei, Xu, Lei, Guan, Wencai, Liu, Yi, Wang, Sen, Shi, Bisheng, Zhang, Wanju, Qin, Boyin, Cai, Jialin, Wan, Yanmin, Xu, Chunhua, Ren, Xiaonan, Chen, Haili, Liu, Lu, Yang, Yuqin, Zhou, Xiaohui, Zhou, Wenjiang, Xu, Jianqing, Zhang, Xiaoyan, Peiris, Malik, Hu, Yunwen, Yuan, Zhenghong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274890/
https://ncbi.nlm.nih.gov/pubmed/26038501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emi.2014.80
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