Formation of a Protein Corona on Silver Nanoparticles Mediates Cellular Toxicity via Scavenger Receptors

Addition of a protein corona (PC) or protein adsorption layer on the surface of nanomaterials following their introduction into physiological environments may modify their activity, bio-distribution, cellular uptake, clearance, and toxicity. We hypothesize that silver nanoparticles (AgNPs) will asso...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Shannahan, Jonathan H., Podila, Ramakrishna, Aldossari, Abdullah A., Emerson, Hilary, Powell, Brian A., Ke, Pu Chun, Rao, Apparao M., Brown, Jared M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Silver Nanoparticle Protein Coating Toxicity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274384/
https://ncbi.nlm.nih.gov/pubmed/25326241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu217
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