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Stimulation of Mucin, Mucus, and Viscosity during Lubiprostone in Patients with Chronic Constipation may Potentially Lead to Increase of Lubrication

OBJECTIVES: The purpose of this clinical trial was to explore whether lubiprostone increases the rate of mucus and mucin secretion and its viscosity in chronic constipation (CC) patients. The secretion of chloride (CS) into the gastrointestinal tract lumen is pivotal in the body's ability to pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Transl Gastroenterol
Hauptverfasser: Majewski, Marek, Sarosiek, Irene, Wallner, Grzegorz, Edlavitch, Stanley A, Sarosiek, Jerzy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274370/
https://ncbi.nlm.nih.gov/pubmed/25521039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2014.19
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