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Oral Immunization with an rfaH Mutant Elicits Protection against Salmonellosis in Mice

Loss of the transcriptional antiterminator RfaH results in virulence attenuation (>10(4)-fold increase in 50% lethal dose) of the archetypal Salmonella enterica serovar Typhimurium strain SL1344 by both orogastric and intraperitoneal routes of infection in BALB/c mice. Oral immunization with the mut...

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Publicat a:Infect Immun
Autors principals: Nagy, Gábor, Dobrindt, Ulrich, Hacker, Jörg, Emödy, Levente
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427435/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15213179/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.7.4297-4301.2004
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