Thyroid hormone regulates muscle fiber type conversion via miR-133a1

It is known that thyroid hormone (TH) is a major determinant of muscle fiber composition, but the molecular mechanism by which it does so remains unclear. Here, we demonstrated that miR-133a1 is a direct target gene of TH in muscle. Intriguingly, miR-133a, which is enriched in fast-twitch muscle, re...

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Vydáno v:J Cell Biol
Hlavní autoři: Zhang, Duo, Wang, Xiaoyun, Li, Yuying, Zhao, Lei, Lu, Minghua, Yao, Xuan, Xia, Hongfeng, Wang, Yu-cheng, Liu, Mo-Fang, Jiang, Jingjing, Li, Xihua, Ying, Hao
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2014
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274265/
https://ncbi.nlm.nih.gov/pubmed/25512392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201406068
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