Oral Tolerance in T Cells Is Accompanied by Induction of Effector Function in Lymphoid Organs after Systemic Immunization

The physiological ramifications of oral tolerance remain poorly understood. We report here that mice fed ovalbumin (OVA) exhibit oral tolerance to subsequent systemic immunization with OVA in adjuvant, and yet they clear systemic infection with a recombinant OVA-expressing strain of Salmonella enter...

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Detalhes bibliográficos
Main Authors: Parameswaran, Neetha, Samuvel, Devadoss John, Kumar, Ramesh, Thatai, Sangeeta, Bal, Vineeta, Rath, Satyajit, George, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC427424/
https://ncbi.nlm.nih.gov/pubmed/15213121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.7.3803-3811.2004
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