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Phenotypic Stability, Matrix Elaboration, and Functional Maturation of Nucleus Pulposus Cells Encapsulated in Photocrosslinkable Hyaluronic Acid Hydrogels

Degradation of the nucleus pulposus (NP) is an early hallmark of intervertebral disc degeneration. The capacity for endogenous regeneration in the NP is limited due to the low cellularity and poor nutrient supply of this avascular tissue. Towards restoring the NP, a number of biomaterials have been...

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Pubblicato in:Acta Biomater
Autori principali: Kim, Dong Hwa, Martin, John T., Elliott, Dawn M., Smith, Lachlan J., Mauck, Robert L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274233/
https://ncbi.nlm.nih.gov/pubmed/25448344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2014.10.030
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