Synthetic Fragments of Vibrio cholerae O1 Inaba O-Specific Polysaccharide Bound to a Protein Carrier Are Immunogenic in Mice but Do Not Induce Protective Antibodies

Development of Vibrio cholerae lipopolysaccharide (LPS) as a cholera vaccine immunogen is justified by the correlation of vibriocidal anti-LPS response with immunity. Two V. cholerae O1 LPS serotypes, Inaba and Ogawa, are associated with endemic and pandemic cholera. Both serotypes induce protective...

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Detalhes bibliográficos
Main Authors: Meeks, Michael D., Saksena, Rina, Ma, Xingquan, Wade, Terri K., Taylor, Ronald K., Kováč, Pavol, Wade, William F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC427411/
https://ncbi.nlm.nih.gov/pubmed/15213154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.7.4090-4101.2004
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