Chronic Exercise Increases Plasma Brain-Derived Neurotrophic Factor Levels, Pancreatic Islet Size, and Insulin Tolerance in a TrkB-Dependent Manner

BACKGROUND: Physical exercise improves glucose metabolism and insulin sensitivity. Brain-derived neurotrophic factor (BDNF) enhances insulin activity in diabetic rodents. Because physical exercise modifies BDNF production, this study aimed to investigate the effects of chronic exercise on plasma BDN...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jiménez-Maldonado, Alberto, de Álvarez-Buylla, Elena Roces, Montero, Sergio, Melnikov, Valery, Castro-Rodríguez, Elena, Gamboa-Domínguez, Armando, Rodríguez-Hernández, Alejandrina, Lemus, Mónica, Murguía, Jesús Muñiz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274083/
https://ncbi.nlm.nih.gov/pubmed/25531651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115177
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