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Atomistic MD simulation reveals the mechanism by which CETP penetrates into HDL enabling lipid transfer from HDL to CETP

Inhibition of cholesterol ester transfer protein (CETP), a protein mediating transfer of neutral lipids between lipoproteins, has been proposed as a means to elevate atheroprotective HDL subpopulations and thereby reduce atherosclerosis. However, off-target and adverse effects of the inhibition have...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Lipid Res
Egile Nagusiak: Cilpa-Karhu, Geraldine, Jauhiainen, Matti, Riekkola, Marja-Liisa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274075/
https://ncbi.nlm.nih.gov/pubmed/25424006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M054288
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