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Antibodies Produced in Response to Cryptococcus neoformans Pulmonary Infection in Mice Have Characteristics of Nonprotective Antibodies

Murine cryptocococcal pulmonary infection elicited serum immunoglobulin M (IgM) and IgG to the capsular polysaccharide, but only IgG stained yeast cells in alveoli. Both isotypes produced punctuate immunofluorescence patterns on yeast cells like those of nonprotective antibodies. The difficulties in...

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Autori principali: Zaragoza, Oscar, Casadevall, Arturo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC427406/
https://ncbi.nlm.nih.gov/pubmed/15213172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.7.4271-4274.2004
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