Yüklüyor......
MicroRNA-7 Inhibits Multiple Oncogenic Pathways to Suppress HER2Δ16 Mediated Breast Tumorigenesis and Reverse Trastuzumab Resistance
The oncogenic isoform of HER2, HER2Δ16, is expressed with HER2 in nearly 50% of HER2 positive breast tumors where HER2Δ16 drives metastasis and resistance to multiple therapeutic interventions including tamoxifen and trastuzumab. In recent years microRNAs have been shown to influence multiple aspect...
Kaydedildi:
| Yayımlandı: | PLoS One |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2014
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4273950/ https://ncbi.nlm.nih.gov/pubmed/25532106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114419 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|