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Toll-like receptor 7-mediated Type I Interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis
Toll-like receptor 7 (TLR7) signaling predominantly regulates production of type I Interferons (IFNs), which has been suggested in clinical studies to be anti-fibrotic. However, the mechanistic role of the TLR7-type I IFN axis in liver fibrosis has not been elucidated. In the present study, liver fi...
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| Publicado en: | Hepatology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4273749/ https://ncbi.nlm.nih.gov/pubmed/24375615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26981 |
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