Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome

BACKGROUND: Despite advances in supportive care, moderate-severe acute respiratory distress syndrome (ARDS) is associated with high mortality rates, and novel therapies to treat this condition are needed. Compelling pre-clinical data from mouse, rat, sheep and ex vivo perfused human lung models supp...

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Vydáno v:Ann Intensive Care
Hlavní autoři: Liu, Kathleen D, Wilson, Jennifer G, Zhuo, Hanjing, Caballero, Lizette, McMillan, Melanie L, Fang, Xiaohui, Cosgrove, Katherine, Calfee, Carolyn S, Lee, Jae-Woo, Kangelaris, Kirsten N, Gotts, Jeffrey E, Rogers, Angela J, Levitt, Joseph E, Wiener-Kronish, Jeanine P, Delucchi, Kevin L, Leavitt, Andrew D, McKenna, David H, Thompson, B Taylor, Matthay, Michael A
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273700/
https://ncbi.nlm.nih.gov/pubmed/25593740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13613-014-0022-z
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