Interplay of cell shapes and oriented cell divisions promotes robust morphogenesis of developing epithelia

Epithelial cells acquire functionally important shapes (e.g., squamous, cuboidal, columnar) during development. Here we combine theory, quantitative imaging, and perturbations to analyze how tissue geometry, cell divisions, and mechanics interact to shape the presumptive enveloping layer (pre-EVL) o...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Xiong, Fengzhu, Ma, Wenzhe, Hiscock, Tom W., Mosaliganti, Kishore R., Tentner, Andrea R., Brakke, Kenneth A., Rannou, Nicolas, Gelas, Arnaud, Souhait, Lydie, Swinburne, Ian A., Obholzer, Nikolaus D., Megason, Sean G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273647/
https://ncbi.nlm.nih.gov/pubmed/25303534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.007
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