Building zinc fingers by selection: toward a therapeutic application.
A phage display approach was utilized to modify the specificity of each of the three fingers of the murine transcription factor Zif268. Selections were performed by using the consensus binding sequence of the natural protein and a conserved sequence in the genome of the type 1 human immunodeficiency...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1995
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42736/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7831288/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.2.344 |
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