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Stabilization of Interferon Messenger RNA Activity by Treatment of Cells with Metabolic Inhibitors and Lowering of the Incubation Temperature

Interferon production was induced in a strain of human diploid foreskin cells with poly(I)·poly(C). Cycloheximide was included in the culture medium at the time of addition of the inducer. Actinomycin D was added to the cultures 4 or 5 hr later, before the inhibition of protein synthesis was reverse...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Vilček, Jan, Havell, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427355/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4544057/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.12.3909
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