Mechanism of Puromycin Action: Fate of Ribosomes after Release of Nascent Protein Chains from Polysomes
The exchange of ribosomal subunits during the release of growing polypeptide chains by puromycin has been investigated in a bacterial cell-free system engaged in protein synthesis. The addition of spermidine, used as a stabilizing agent of 70S monomers, caused a strong inhibition of the subunit exch...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1973
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427346/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4590173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.12.3866 |
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