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Full-length structure of a monomeric histidine kinase reveals basis for sensory regulation

Although histidine kinases (HKs) are critical sensors of external stimuli in prokaryotes, the mechanisms by which their sensor domains control enzymatic activity remain unclear. Here, we report the full-length structure of a blue light-activated HK from Erythrobacter litoralis HTCC2594 (EL346) and t...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Rivera-Cancel, Giomar, Ko, Wen-huang, Tomchick, Diana R., Correa, Fernando, Gardner, Kevin H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273353/
https://ncbi.nlm.nih.gov/pubmed/25468971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413983111
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