Preparation of neuroprotective condensed 1,4-benzoxazepines by regio- and diastereoselective domino Knoevenagel–[1,5]-hydride shift cyclization reaction

Condensed O,N-heterocycles containing tetrahydro-1,4-benzoxazepine and tetrahydroquinoline moieties were prepared by a regio- and diastereoselective domino Knoevenagel–[1,5]-hydride shift cyclization reaction of a 4-aryl-2-phenyl-1,4-benzoxazepine derivative obtained from flavanone. The relative con...

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Pubblicato in:Beilstein J Org Chem
Autori principali: Tóth, László, Fu, Yan, Zhang, Hai Yan, Mándi, Attila, Kövér, Katalin E, Illyés, Tünde-Zita, Kiss-Szikszai, Attila, Balogh, Balázs, Kurtán, Tibor, Antus, Sándor, Mátyus, Péter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2014
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Letter
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273254/
https://ncbi.nlm.nih.gov/pubmed/25550721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.272
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