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A Randomized Double-Blind Placebo-Controlled Dose-Escalation Phase 1 Study of Aerosolized Amikacin and Fosfomycin Delivered via the PARI Investigational eFlow(®) Inline Nebulizer System in Mechanically Ventilated Patients

Background: This clinical trial evaluated the pharmacokinetics and safety/tolerability of amikacin/fosfomycin solution using a vibrating plate nebulizer, in mechanically ventilated patients with ventilator-associated tracheobronchitis (VAT) or ventilator-associated pneumonia (VAP). Methods: Nine adu...

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Detalhes bibliográficos
Publicado no:J Aerosol Med Pulm Drug Deliv
Main Authors: Montgomery, A. Bruce, Vallance, Shirley, Abuan, Tammy, Tservistas, Markus, Davies, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273204/
https://ncbi.nlm.nih.gov/pubmed/24383962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jamp.2013.1100
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