Immune mechanisms in acetaminophen-induced acute liver failure

An overdose of acetaminophen (N-acetyl-p-aminophenol, APAP), also termed paracetamol, can cause severe liver damage, ultimately leading to acute liver failure (ALF) with the need of liver transplantation. APAP is rapidly taken up from the intestine and metabolized in hepatocytes. A small fraction of...

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Udgivet i:Hepatobiliary Surg Nutr
Main Authors: Krenkel, Oliver, Mossanen, Jana C., Tacke, Frank
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2014
Fag:
Review Article: Liver Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273118/
https://ncbi.nlm.nih.gov/pubmed/25568858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2304-3881.2014.11.01
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