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Investigation of Channel-Forming Activity of Polyene Macrolide Antibiotics in Planar Lipid Bilayers in the Presence of Dipole Modifiers

The role of membrane components, sterols, phospholipids and sphingolipids in the formation and functioning of ion-permeable nanopores formed by antifungal macrolide antibiotics, amphotericin B, nystatin and filipin in planar lipid bilayers was studied. Dipole modifiers, flavonoids and styryl dyes, w...

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Bibliographic Details
Published in:Acta Naturae
Main Authors: Efimova, S. S., Schagina, L. V., Ostroumova, O. S.
Format: Artigo
Language:Inglês
Published: A.I. Gordeyev 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273094/
https://ncbi.nlm.nih.gov/pubmed/25558397
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