Early Differentiation of Glucagon-Producing Cells in Embryonic Pancreas: A Possible Developmental Role for Glucagon

Glucagon and insulin are first detectable at the onset of rat pancreas organogenesis. Initially, the specific activity of glucagon is approximately 100-fold higher than that of insulin. At this early stage, endocrine storage granules, similar to α granules, are identifiable in electron micrographs....

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Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Rall, Leslie B., Pictet, Raymond L., Williams, Robert H., Rutter, William J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1973
Schlagworte:	Biological Sciences: Biochemistry
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427263/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4519640/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.12.3478
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