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Peptide Macrocyclization Catalyzed by a Prolyl Oligopeptidase Involved in α-Amanitin Biosynthesis
Amatoxins are ribosomally-encoded and post-translationally modified peptides (RiPPs) that account for the majority of fatal mushroom poisonings of humans. A representative amatoxin is the bicyclic octapeptide α-amanitin formed via head-to-tail macrocyclization, which is ribosomally biosynthesized a...
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| 出版年: | Chem Biol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272623/ https://ncbi.nlm.nih.gov/pubmed/25484237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.10.015 |
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