Genomic locus on chromosome 1 regulates susceptibility to spontaneous arthritis in mice deficiency of IL-1RA

BACKGROUND: To understand the role of genetic factors on chromosome 1 in the regulation of spontaneous arthritis in mice deficient in IL-1 receptor antagonist protein (IL_1RA), we previously used speed congenic breeding to transfer the QTL region from DBA/1(−/−) mice that are resistant to spontaneou...

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Publicat a:BMC Immunol
Autors principals: Deng, Nan, Jiao, Yan, Cao, Yanhong, Liu, Xiaoyun, Ma, Yonghui, Hasty, Karen A, Brand, David D, Stuart, John M, Gu, Weikuan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272550/
https://ncbi.nlm.nih.gov/pubmed/25488730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-014-0057-9
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