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The acetate switch of an intestinal pathogen disrupts host insulin signaling and lipid metabolism
Vibrio cholerae is lethal to the model host Drosophila melanogaster through mechanisms not solely attributable to cholera toxin. To examine additional virulence determinants, we performed a genetic screen in V. cholerae-infected Drosophila and identified the two-component system CrbRS. CrbRS control...
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Publicado no: | Cell Host Microbe |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272434/ https://ncbi.nlm.nih.gov/pubmed/25525791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.10.006 |
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