Impact of Glutathione S-Transferase M1 and T1 on Anti-Tuberculosis Drug–Induced Hepatotoxicity in Chinese Pediatric Patients

BACKGROUND: Anti-tuberculosis drug induced hepatotoxicity (ATDH) is a major adverse drug reaction associated for anti-tuberculosis therapy. The glutathione S-transferases (GST) plays a crucial role in the detoxification of hepatotoxic metabolites of anti-tuberculosis drugs.An association between GST...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Fang, Jiao, An-xia, Wu, Xi-rong, Zhao, Wei, Yin, Qing-qin, Qi, Hui, Jiao, Wei-wei, Xiao, Jing, Sun, Lin, Shen, Chen, Tian, Jian-ling, Shen, Dan, Jacqz-Aigrain, Evelyne, Shen, A-dong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272297/
https://ncbi.nlm.nih.gov/pubmed/25525805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115410
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