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A Human-specific Mutation Limits Nonhuman Primate Efficacy in Preclinical Xenotransplantation Studies

BACKGROUND: Patients diagnosed with fulminant hepatic failure face high mortality rates. A potential therapeutic approach for these patients is the use of extracorporeal porcine liver perfusion, to serve as a form of “liver dialysis”. Previously, our laboratory has shown that, during a 72 hour extra...

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Foilsithe in:Transplantation
Main Authors: Waldman, Joshua P., Brock, Linda G., Rees, Michael A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271973/
https://ncbi.nlm.nih.gov/pubmed/24445925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.TP.0000441321.87915.82
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