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Selective gelatinase inhibition reduces apoptosis and pro-inflammatory immune cell responses in Campylobacter jejuni-infected gnotobiotic IL-10 deficient mice

Increased levels of the matrix metalloproteinases-2 and -9 (also referred to gelatinase-A and -B, respectively) can be detected in intestinal inflammation. We have recently shown that selective gelatinase blockage by the synthetic compound RO28-2653 ameliorates acute murine ileitis and colitis. We h...

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Foilsithe in:Eur J Microbiol Immunol (Bp)
Main Authors: Alutis, M. E., Grundmann, U., Fischer, A., Kühl, A. A., Bereswill, S., Heimesaat, M. M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Akadémiai Kiadó 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271818/
https://ncbi.nlm.nih.gov/pubmed/25544894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1556/EUJMI-D-14-00031
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