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A Mammalian Cell Mutant with a Temperature-Sensitive Leucyl-Transfer RNA Synthetase

A cell mutant of the Chinese hamster ovary line, which is temperature sensitive for protein synthesis, is specifically defective in vivo in its ability to charge tRNA with leucine. Cytoplasmic extracts exhibited temperature-sensitive leucyl-tRNA synthetase activity. It is, therefore, highly likely t...

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Detalhes bibliográficos
Main Authors: Thompson, L. H., Harkins, J. L., Stanners, C. P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC427177/
https://ncbi.nlm.nih.gov/pubmed/4361675
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