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D-Glyceraldehyde-3-Phosphate Dehydrogenase: Three-Dimensional Structure and Evolutionary Significance

A 3.0-Å resolution electron density map of lobster glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) was computed. The essentially single isomorphous replacement map was very substantially improved by averaging subunits. NAD binds in an open conformation at sites close to subunit interfaces. Th...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Buehner, Manfred, Ford, Geoffrey C., Moras, Dino, Olsen, Kenneth W., Rossmann, Michael G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1973
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Biological Sciences: Biochemistry
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4361672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.11.3052
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