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Crystal structure of the C-terminal domain of mouse TLR9

Toll-like receptors (TLRs) are important pattern recognition receptors that function in innate immunity. Elucidating the structure and signaling mechanisms of TLR9, a sensor of foreign and endogenous DNA, is essential for understanding its critical roles in immunity and autoimmunity. Abundant eviden...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Collins, Bernard, Wilson, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271629/
https://ncbi.nlm.nih.gov/pubmed/24888966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24616
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