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A Systematic Survey of an Intragenic Epistatic Landscape
Mutations are the source of evolutionary variation. The interactions of multiple mutations can have important effects on fitness and evolutionary trajectories. We have recently described the distribution of fitness effects of all single mutations for a nine-amino-acid region of yeast Hsp90 (Hsp82) i...
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| Veröffentlicht in: | Mol Biol Evol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4271534/ https://ncbi.nlm.nih.gov/pubmed/25371431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msu301 |
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