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The molecular mechanism underlying formation of deletions in Fanconi anemia cells may involve a site-specific recombination.

Spontaneous and induced chromosomal breakage is an important cellular feature of Fanconi anemia (FA), an inherited DNA repair disorder characterized by progressive bone marrow failure, developmental abnormalities, and predisposition to leukemia. We have previously reported that in comparison to norm...

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Bibliografische gegevens
Hoofdauteurs: Laquerbe, A, Moustacchi, E, Fuscoe, J C, Papadopoulo, D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1995
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC42714/
https://ncbi.nlm.nih.gov/pubmed/7846061
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