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The Anti-proliferative Function of the TGF-β1 Signaling Pathway Involves the Repression of the Oncogenic TBX2 by Its Homologue TBX3

A growing body of work has shown that the highly homologous T-box transcription factors TBX2 and TBX3 play critical but distinct roles in embryonic development and cancer progression. For example, TBX2 and TBX3 are up-regulated in several cancers and recent evidence suggests that whereas TBX2 functi...

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Vydáno v:J Biol Chem
Hlavní autoři: Li, Jarod, Ballim, Deeya, Rodriguez, Mercedes, Cui, Rutao, Goding, Colin R., Teng, Huajian, Prince, Sharon
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271245/
https://ncbi.nlm.nih.gov/pubmed/25371204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.596411
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