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A Conserved Three-nucleotide Core Motif Defines Musashi RNA Binding Specificity

Musashi (MSI) family proteins control cell proliferation and differentiation in many biological systems. They are overexpressed in tumors of several origins, and their expression level correlates with poor prognosis. MSI proteins control gene expression by binding RNA and regulating its translation....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Zearfoss, N. Ruth, Deveau, Laura M., Clingman, Carina C., Schmidt, Eric, Johnson, Emily S., Massi, Francesca, Ryder, Sean P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271237/
https://ncbi.nlm.nih.gov/pubmed/25368328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.597112
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