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Human Macrophage SCN5A Activates an Innate Immune Signaling Pathway for Antiviral Host Defense
Pattern recognition receptors contain a binding domain for pathogen-associated molecular patterns coupled to a signaling domain that regulates transcription of host immune response genes. Here, a novel mechanism that links pathogen recognition to channel activation and downstream signaling is propos...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4271219/ https://ncbi.nlm.nih.gov/pubmed/25368329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.611962 |
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