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Constitutive Activation of MEK1 Promotes Treg Cell Instability in Vivo

The instability of regulatory T (Treg) cells is involved in the pathogenesis of autoimmune diseases and also highlights safety concerns with regard to clinical Treg cell therapy. Cell-intrinsic molecular events linked to this Treg cell instability in vivo cells, which leads to safety concerns regard...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Guo, Jitao, Zhang, Jianhua, Zhang, Xuejie, Zhang, Zhongmei, Wei, Xundong, Zhou, Xuyu
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271203/
https://ncbi.nlm.nih.gov/pubmed/25361764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589192
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