Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis.

Atherosclerotic lesions contain oxidized LDL (OxLDL), immunoglobulins, and immune-competent cells. Low levels of circulating autoantibodies against malondialdehyde (MDA)-modified lysine, an epitope of OxLDL, occur in several species, and immune complexes between such autoantibodies and OxLDL are pre...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Palinski, W, Miller, E, Witztum, J L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42712/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7846059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.821
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