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Loss of α(E)-Catenin Potentiates Cisplatin-Induced Nephrotoxicity via Increasing Apoptosis in Renal Tubular Epithelial Cells

Cisplatin is one of the most potent and widely used antitumor drugs. However, the use of cisplatin is limited by its side effect, nephrotoxicity. Evidence has shown an increased incidence and severity of acute kidney injury (AKI) in the elderly. Previous studies from our laboratory demonstrate a dec...

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Publicat a:Toxicol Sci
Autors principals: Wang, Xinhui, Grunz-Borgmann, Elizabeth A., Parrish, Alan R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271126/
https://ncbi.nlm.nih.gov/pubmed/24973089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu130
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