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Human Phosphoribosylpyrophosphate Synthetase: Increased Enzyme Specific Activity in a Family with Gout and Excessive Purine Synthesis

Among affected members of a family (B. family) with excessive purine production and gout, activity of phosphoribosylpyrophosphate synthetase (EC 2.7.6.1) is 2.5- to 3.0-fold higher than among normal people. The molecular basis for this increased enzyme activity was studied. Antibody to purified huma...

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Detaylı Bibliyografya
Asıl Yazarlar: Becker, Michael A., Kostel, Paul J., Meyer, Laurence J., Seegmiller, J. Edwin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1973
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC427101/
https://ncbi.nlm.nih.gov/pubmed/4200723
Etiketler: Etiketle
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