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Progesterone and allopregnanolone improve stroke outcome in male mice via distinct mechanisms but neither promotes neurogenesis

Based on the outcome of a number of experimental studies, progesterone holds promise as a new therapy for stroke. To understand more about the mechanisms involved we administered progesterone (or the major metabolite, allopregnanolone), intra-peritoneally, for a period of 24 h after transient middle...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Lee, Rona J., Kim, Joon K., Chao, Diana, Kuo, Lisa, Mally, Adheip, McClean, Megan E., Pemberton, Heather E., Wilmington, Andrew R., Wong, Jennifer, Murphy, Sean P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270875/
https://ncbi.nlm.nih.gov/pubmed/25376903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12990
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