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Synthesis and Aminoacylation of 3′-Amino-3′-deoxy Transfer RNA and Its Activity in Ribosomal Protein Synthesis

3′-amino-3′-deoxy adenosine was enzymatically converted into 3′-amino-3′-deoxy ATP. This ATP analogue was incorporated into the 3′-terminal adenosine position of Escherichia coli tRNA. The modified tRNA was aminoacylated with phenylalanine by use of E. coli phenylalanyl tRNA synthetase. The phenylal...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Fraser, Thomas H., Rich, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427080/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4582194/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.9.2671
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