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Membrane Morphology Is Actively Transformed by Covalent Binding of the Protein Atg8 to PE-Lipids
Autophagy is a cellular degradation pathway involving the shape transformation of lipid bilayers. During the onset of autophagy, the water-soluble protein Atg8 binds covalently to phosphatdylethanolamines (PEs) in the membrane in an ubiquitin-like reaction coupled to ATP hydrolysis. We reconstituted...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270758/ https://ncbi.nlm.nih.gov/pubmed/25522362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115357 |
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