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Differential NF-κB and MAPK activation underlies fluoride- and TPA-mediated CXCL8 (IL-8) induction in lung epithelial cells

Different toxic agents have a varying potential to induce the production of the proinflammatory chemokine, CXCL8 (interleukin [IL]-8), in lung cells. A critical question is which mechanisms determine the magnitude and persistence of the CXCL8 responses to different stimuli. To approach this, we comp...

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Detalles Bibliográficos
Publicado en:J Inflamm Res
Main Authors: Refsnes, Magne, Skuland, Tonje, Låg, Marit, Schwarze, Per E, Øvrevik, Johan
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270361/
https://ncbi.nlm.nih.gov/pubmed/25540590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S69646
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