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Sample Size Requirements and Study Duration for Testing Main Effects and Interactions in Completely Randomized Factorial Designs When Time to Event is the Outcome
In this paper we develop the methodology for designing clinical trials with any factorial arrangement when the primary outcome is time to event. We provide a matrix formulation for calculating the sample size and study duration necessary to test any effect with a pre-specified type I error rate and...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Commun Stat Theory Methods |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270194/ https://ncbi.nlm.nih.gov/pubmed/25530661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03610926.2012.705940 |
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