High Dose Simvastatin Exhibits Enhanced Lipid Lowering Effects Relative to Simvastatin/Ezetimibe Combination Therapy

Statins are the frontline in cholesterol reduction therapies; however use in combination with agents that possess complimentary mechanisms of action may achieve further reductions in LDL-C. Thirty-nine patients were treated with either 80mg simvastatin (n=20) or 10mg simvastatin plus 10mg ezetimibe...

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Veröffentlicht in:Circ Cardiovasc Genet
Hauptverfasser: Snowden, Stuart G., Grapov, Dmitry, Settergren, Magnus, D'Alexandri, Fabio Luiz, Haeggström, Jesper Z., Fiehn, Oliver, Hyötyläinen, Tuulia, Pedersen, Theresa L., Newman, John W., Orešič, Matej, Pernow, John, Wheelock, Craig E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270085/
https://ncbi.nlm.nih.gov/pubmed/25516625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.114.000606
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