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Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4
Lrp4, the muscle receptor for neuronal Agrin, is expressed in the hippocampus and areas involved in cognition. The function of Lrp4 in the brain, however, is unknown, as Lrp4(−/−) mice fail to form neuromuscular synapses and die at birth. Lrp4(−/−) mice, rescued for Lrp4 expression selectively in mu...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270049/ https://ncbi.nlm.nih.gov/pubmed/25407677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04287 |
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