Mycophenolic acid AUC in Thai kidney transplant recipients receiving low dose mycophenolate and its association with UGT2B7 polymorphisms

BACKGROUND: Despite use of a lower mycophenolate dose in Thai kidney transplant patients, acceptable graft and patient outcomes can be achieved. We therefore examined the pharmacokinetics of mycophenolic acid (MPA) by area under the curve (AUC) and investigated genetic contribution in mycophenolate...

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Veröffentlicht in:Pharmgenomics Pers Med
Hauptverfasser: Pithukpakorn, Manop, Tiwawanwong, Tiwat, Lalerd, Yupaporn, Assawamakin, Anunchai, Premasathian, Nalinee, Tasanarong, Adis, Thongnoppakhun, Wanna, Vongwiwatana, Attapong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2014
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270037/
https://ncbi.nlm.nih.gov/pubmed/25540593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S72760
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